Steroids and derivatives
Cambridge Isotope Laboratories DL-Estrone 3-methyl ether (13 14 15 16 17 18-13C6 99%) 0 1 mg
DL-Estrone 3-methyl ether (13 14 15 16 17 18-13C6 99%) 0 1 mg
Medchemexpress LLC Estradiol benzoate | 50-50-0 | 99.9% | 250 MG
Estradiol benzoate is a HBx protein inhibitor that inhibits androgen and hepatitis B virus (HBV) transcription and replication. It also shows antifertility effects, anti-Toxoplasma gondii activity, and can improve memory behavior in Ovariectomy (Ovx) female mice.
- Inhibits HBx protein
- Inhibits androgen transcription
- Inhibits hepatitis B virus (HBV) transcription and replication
- Exhibits antifertility effects
- Shows anti-Toxoplasma gondii activity
- May improve memory behavior in Ovariectomy (Ovx) female mice
Cayman Chemical Estradiol Benzoate
An estradiol analog; often used in combination with a progestin to induce estrus in domestic livestock; binds to human, murine, and chicken ERα IC50s = 22-28 nM)
eMolecules 142878-12-4 | Medchem Express | U-73343 | 5mg | 482203907 | HY-108630 | 466.666 | C29H42N2O3
Ambeed | 57-Dimethyl-N-(trans-4-(pentyloxy)cyclohexyl)pyrazolo[15-a]pyrimidine-3-carboxamide | 1mg | 534567031 | A181720 | 1919820-28-2 | 358.486 | C20H30N4O2
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Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.88% | C32H38N2O5 | 500 MG
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM). It has IC50s of 23 nM for ERα and 99 nM for ERβ. This compound is used in the research of osteoporosis. Additionally, Bazedoxifene acetate acts as an inhibitor of IL-6/GP130 protein-protein interactions and is utilized in research for pancreatic cancer.
- Oral, nonsteroidal selective estrogen receptor modulator (SERM)
- Exhibits IC50s of 23 nM for ERα and 99 nM for ERβ
- Used in osteoporosis and pancreatic cancer research
- Inhibits IL-6/GP130 protein-protein interactions and STAT3 phosphorylation
- Induces apoptosis and blocks cell migration in pancreatic cancer cells in vitro
- Inhibits Capan-1 tumor growth in a mouse model in vivo
Medchemexpress LLC Paramethasone acetate | 1597-82-6 | 98.0% | 434.50 g/mol | C24H31FO6 | 10 MG
Paramethasone acetate is a synthetic glucocorticoid acetate supplied as a solid research reagent with reported purity of 98% and a molecular weight of 434.50 g/mol. It is used in research to study anti-inflammatory and immunosuppressive effects, glucocorticoid receptor activity, and related signaling pathways. Storage recommendations and an SDS are provided for safe handling and stability considerations.
- High listed purity suitable for research applications.
- Supplied as a solid powder for precise dosing and solution preparation.
- Useful for in vitro and preclinical studies of glucocorticoid activity.
- Provides storage and stability guidance for powder and solutions.
- Accompanied by safety data and documentation for laboratory use.
Apexbio Technology LLC Medroxyprogesterone acetate 71-58-9 10mM (in 1mL DMSO)
Medroxyprogesterone acetate (MPA) is a synthetic steroidal derivative structurally related to the endogenous hormone progesterone classified as a progestin Acting primarily through binding to progesterone receptors it modulates gene transcription influencing endometrial proliferation and reproductive pathways Additionally MPA exhibits affinity toward glucocorticoid receptors which may contribute to its physiological effects In biomedical research MPA serves as a standard experimental tool to investigate progesterone receptor signaling mechanisms and steroid hormone interactions Furthermore it is widely used in studies focused on reproductive biology contraceptive mechanisms hormone replacement therapy models oncology research involving hormone-responsive tumors and conditions such as endometriosis
Medchemexpress LLC Paramethasone acetate | 1597-82-6 | MFCD00200359 | 98.0% | 434.50 g·mol⁻¹ | C24H31FO6 | 5 MG
Paramethasone acetate is a synthetic glucocorticoid acetate ester supplied for research use. It shows anti-inflammatory and immunosuppressant activity and is provided as a solid reagent for laboratory and analytical applications. Safety data and handling information are available in the SDS and supporting documentation.
- Exhibits anti-inflammatory and immunosuppressant activity.
- Acetate ester form suitable for standard biochemical assays.
- High purity (98.0%) for reproducible research results.
- Solid, white to light yellow appearance simplifies storage and handling.
- Available in small research quantities (e.g., 5 mg).
- SDS and safety documentation available for laboratory compliance.
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 99.5% | 1006.63 | 10 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits high affinity for both human (hV2R) and rat (rV2R) V2 receptors, with EC50s of 0.07 nM and 0.02 nM respectively. This product is intended for research purposes only.
- Potent and selective V2 receptor agonist
- Short-acting peptidic compound
- High affinity for human and rat V2 receptors
- For research purposes only
Apexbio Technology LLC Deoxycorticosterone acetate 56-47-3 50mg
Deoxycorticosterone acetate (56-47-3) is a small-molecule agonist targeting mineralocorticoid receptors (MR) It is designed to activate MR thereby regulating renal sodium reabsorption and potassium excretion Deoxycorticosterone acetate exerts its biological activity primarily through interaction with cytoplasmic mineralocorticoid receptors leading to nuclear translocation and modulation of electrolyte balance Typical IC50 values associated with its mineralocorticoid receptor binding affinity have been reported in the nanomolar range Based on these pharmacological properties Deoxycorticosterone acetate holds research potential in studies of electrolyte balance adrenal insufficiency modeling and the pathophysiology of hypertension as well as models investigating mineralocorticoid receptor-dependent signaling and renal or cardiovascular physiology
Apexbio Technology LLC Medroxyprogesterone 520-85-4 50mg
Medroxyprogesterone (CAS 520-85-4) is a small-molecule agonist targeting the progesterone receptor It is designed to activate progesterone receptor-mediated intracellular signaling pathways thereby regulating cellular proliferation Medroxyprogesterone exerts its biological activity primarily through agonism of the progesterone receptor modulating pathways such as PI3K/Akt signaling In preclinical mouse models medroxyprogesterone demonstrates inhibitory activity on atherosclerotic lesion formation Based on these pharmacological properties medroxyprogesterone holds research potential in the study of progesterone receptor-mediated biological processes cellular proliferation and vascular pathology
