Steroids and derivatives
Apexbio Technology LLC α-Estradiol 57-91-0 50mg
alpha-Estradiol (57-91-0) is a small-molecule inhibitor targeting 5 -reductase the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) It is designed to inhibit 5 -reductase activity thereby modulating androgen metabolism and androgen-related signaling pathways alpha-Estradiol exerts its biological activity primarily through enzyme inhibition In reported experimental studies alpha-Estradiol demonstrates inhibitory activity against 5 -reductase with an IC50 value ranging from approximately 1 to 10 M though the precise value may depend on assay conditions Based on these pharmacological properties alpha-Estradiol holds research potential in the treatment and study of androgenetic alopecia
Medchemexpress LLC Estradiol-d3 | 79037-37-9 | MFCD01074033 | 99.8% | 1 MG
Estradiol-d3 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 17β-Estradiol-13C3 | 1261254-48-1 | 98.1% | C1513C3H24O2 | 1 MG
17β-Estradiol-13C3 is the 13C labeled version of 17β-Estradiol. It is intended for research use only and is not sold to patients. The incorporation of stable heavy isotopes into drug molecules is primarily done for quantitation tracing during the drug development process. The molecular weight of 17β-Estradiol-13C3 is 275.36 and it appears as a white to off-white solid.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical 1-hydroxy VItamIn D2 1mg
A synthetic prodrug of 1,25-dihydroxy vitamin D2; used to suppress the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; stimulates bone growth; inhibits the growth of certain blastomas and prostate cancer cells
Medchemexpress LLC Ofloxacin-d3 | 1173147-91-5 | 99.8% | 1 MG
Ofloxacin-d3 is a deuterium-labeled form of Ofloxacin designed for research applications. It serves as a tracer and an internal standard, facilitating quantitative analysis in methods like NMR, GC-MS, or LC-MS. This compound leverages stable heavy isotopes, which are incorporated into drug molecules to aid quantitation during drug development and may influence pharmacokinetic and metabolic profiles.
- Deuterium labeled Ofloxacin.
- Intended for research use only.
- Functions as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Ofloxacin-d3 | 1173147-91-5 | 99.8% | 5 MG
Ofloxacin-d3 is the deuterium labeled Ofloxacin.
- Used for research purposes only.
- Can be utilized as a tracer.
- Serves as an internal standard for quantitative analysis through NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes (deuterium) for quantitation during drug development.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Classified as an isotope-labeled compound and a hot research area.
- Can be used as an internal standard for clinical mass spectrometry, food, pesticides, and veterinary medicine.
- Isotope-labeled inhibitors and stable isotope-labeled inhibitors for in vivo cell experiments.
- Relevant for therapeutic drug monitoring (TDM).
Cayman Chemical 25-hydroxy VItamIn D3 1mg
An intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D3; plasma or serum levels are commonly used as an indicator of an individual’s vitamin D status
eMolecules 134404-52-7 | Medchem Express | Seocalcitol | 1mg | 446270827 | HY-32341 | MFCD00871599 | 454.695 | C30H46O3
Ambeed | tert-Butyl (6-chloro-3-iodopyridin-2-yl)carbamate | 250mg | 490538910 | A228018 | 1622407-12-8 | MFCD13196667 | 354.570 | C10H12ClIN2O2
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Medchemexpress LLC 2-Nonenal-9,9,9-d3, 4-hydroxy-, (E)- | 148706-06-3 | 99.0% | 159.24 | 50 UG
4-Hydroxynonenal-d3 is the deuterium labeled form of 4-Hydroxynonenal (4-HNE), an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. It acts as both a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). This compound modulates signaling processes by forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids, and plays an important role in cancer through mitochondria.
- Functions as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stored as a solution at -20°C, protected from light, for up to 2 years.
- For research use only.
- Deuterium labeling can influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Vinorelbine-d3 ditartrate | 125317-39-7 | 98.0% | 1082.12 | 1 MG
Vinorelbine-d3 (ditartrate) is the deuterium labeled Vinorelbine ditartrate. Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.